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| leghisturl = http://thomas.loc.gov/cgi-bin/bdquery/z?d095:SN01750:@@@R | introducedin = Senate | introducedbill = | introducedby = Edward M. Kennedy (D-MA) | introduceddate = June 23, 1977 | committees = Senate Human Resources, Senate Commerce, Science, and Transportation, House Interstate and Foreign Commerce | passedbody1 = Senate | passeddate1 = September 15, 1977 | passedvote1 = (87-7 ) | passedbody2 = House | passedas2 = | passeddate2 = October 17, 1977 | passedvote2 = (375-23 ), in lieu of | conferencedate = November 3, 1977 | passedbody3 = House | passeddate3 = November 3, 1977 | passedvote3 = agreed | agreedbody3 = | agreeddate3 = | agreedvote3 = | agreedbody4 = | agreeddate4 = | agreedvote4 = | passedbody4 = Senate | passeddate4 = November 4, 1977 | passedvote4 = agreed | signedpresident = Jimmy Carter | signeddate = November 23, 1977 | unsignedpresident = | unsigneddate = | vetoedpresident = | vetoeddate = | overriddenbody1 = | overriddendate1 = | overriddenvote1 = | overriddenbody2 = | overriddendate2 = | overriddenvote2 = | amendments = | SCOTUS cases = }} Saccharin Study and Labeling Act of 1977 or Saccharin Study, Labeling and Advertising Act was a United States federal statute enacting requirements for a scientific observation regarding the impurities in, potential toxicity, and problematic carcinogenicity of a non-nutritive sweetener better known as saccharin. The Act of Congress invoked an immediate eighteen month moratorium prohibiting the Secretary of Health, Education, and Welfare from pursuing regulatory implications by limiting the production and use of saccharin. The Act codified a warning label requirement advocating the non-nutritive sweetener had been discovered to yield carcinogenicity in laboratory animals. The S. 1750 legislation was passed by the 95th Congressional session and signed into law by the 39th President of the United States Jimmy Carter on November 23, 1977. ==Research Perspective== In 1948 to 1949, U.S. Food and Drug Administration pathologists conducted laboratory analyses on Osborne-Mendel rat specimens concluding lymphosarcoma after a two year laboratory analysis. In 1951, scientists collaboratively suggested the white crystalline sweetening agent could be a possible carcinogen. In 1958, saccharin was registered Generally Recognized As Safe (GRAS) by decree of the food additives amendment retaining the non-nutritive sweetener as a marketable product for human consumption. In 1972 to 1973 after much growing concern among the United States population, the U.S. Food and Drug Administration and Wisconsin Alumni Research Foundation (WARF) led carcinogenic studies concluding the incidence of bladder tumors in Charles River Sprague-Dawley rat specimens. As a result of the laboratory analyses, the U.S. Food and Drug Administration revoked the Generally Recognized As Safe (GRAS) classification and imposed regulatory procedures restricting the use of saccharin in food products. In 1974, the National Academy of Sciences published a scientific review emphasizing saccharin could not be identified as the carcinogenic agent of benign tumors and malignant tumors due to equivocal analysis procedures, inadequate scientific experimental design, and potential impurities. In 1977, the Canadian Health Protection Branch Study was completed on Charles River Sprague-Dawley rat specimens concluding lymphoma in the blood cells.〔(【引用サイトリンク】title=New Canadian Study Connects Sweeteners With Cancer in Men )〕〔(【引用サイトリンク】title=F.D.A. Says New Canadian Study Reinforces Its Ban of Saccharin )〕 The Canadian carcinogenic study encouraged Canada to remove saccharin as a marketable product for human consumption in 1977. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Saccharin Study and Labeling Act of 1977」の詳細全文を読む スポンサード リンク
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